Ideas alone are good but not good enough – it takes collaboration to make things happen. That theme was heard throughout UC Global Health Day 2014, including in the morning plenary featuring Jonna Mazet, Executive Director of the One Health Institute and Andrew Hargadon of the Graduate School of Management at UC Davis. Drs. Mazet and Hargadon explored the discovery of penicillin, why this lifesaving antibiotic took so long to get to market, and what steps must be taken to advance the pace of global health innovation. UC Global Health Day was sponsored by the UC Global Health Institute.