FGF Signaling and Neocortical Patterning

FGF Signaling and Neocortical Patterning

First Aired: 12/8/2009

Length: 52 minutes


Fibroblast growth factors and development.
 
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Fibroblast growth factors, or FGFs are a family of growth factors that are important for normal embryonic development. There are over 20 members of the FGF family. Dr. John Rubenstein of UCSF explores several members of the FGF family, including FGF-8 and FGF-17, and discuss how these molecules are required for normal development of the cerebral cortex. He discusses FGFs that play a role in neocortical development, transcription factors that regulate FGF signaling in the cerebral cortex, and implications for autism spectrum disorders.
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